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KMID : 1103920060120030318
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Korean Journal of Hepatology
2006 Volume.12 No. 3 p.318 ~ p.322
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Autoimmune Hepatitis: Recent Update on Diagnosis and Treatment
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Lee Yung-Sang
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Abstract
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Autoimmune hepatitis (AIH) is an unresolving, predominantly periportal hepatitis that is usually displays
hypergammaglobulinemia, and tissue autoantibodies, and this malady is responsive to immunosuppressive
therapy. Our understanding about this clinical entity has been greatly expanded since the first description by
Waldenstrom 50 years ago. The codified diagnostic criteria of AIH prepared by International Autoimmune
Hepatitis Group are still valid, but new attempts are being made to overcome the shortcomings of this scoring
system. Immunosuppressive therapies using prednisone and azathioprine are currently the mainstay for the
treatment of AIH, but there are still many practical questions to be solved.
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KEYWORD
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Autoimmune hepatitis, Diagnosis, Treatment, Prognosis
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